Caryn Talty Why am I so Edgy? Learn about Pyrrole Disorder (Pyroluria).

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Are you easily agitated and a chronic insomniac, often waking up in the morning after what seems like a very short, dreamless night? Perhaps you’re one of those people that never eats breakfast; instead you prefer to race off to work or school. Do you often forget where you just put something or what someone just told you? Maybe you also have a hankering for spicy foods and a huge gut to match. If you have a hard time handling stress, find most of these statements to be true about yourself and you are often unhappy or depressed it may be due to highly under-diagnosed vitamin/mineral imbalance called Pyrrole Disorder.

The symptoms of Pyrrole disorder or Pyroluria vary but may include:

  • lack of dream recall
  • white spots on nails
  • dislikes loud noises or bright lights
  • problems with menstrual cycle or sex problems
  • problems with depression
  • pale skin, skin that easily burns
  • insomnia
  • stunted growth, late growth spurt
  • prone to temper outbursts
  • likes spicy foods
  • better long-term than short-term memory
  • reading difficulties
  • ADHD (Attention Deficit Hyperactivity Disorder) symptoms
  • anemia (low iron)
  • protruding abdomen
  • delayed puberty

In severe cases other disorders may be present as well such as: OCD (Obsessive-Compulsive Disorder), Bipolar Disorder, severe depression, Tourette Syndrome, Schizophrenia, Autism, etc…

Through a simple urinary test this hereditary chemical imbalance can be diagnosed. It is treatable by taking a specified amount of Vitamin C, Vitamin E, Vitamin B6, Vitamin B5, Magnesium, and Zinc. Primrose oil or Borage oil is also sometimes included, as are various amino acids depending on the presence of associated disorders.

Pyroluria is another term for pyrrole disorder. A genetic condition, Pyroluria causes anxiety, depression and withdrawal. Sufferers can be any age, although most are not diagnosed until adulthood. Symptoms can be very severe or very mild and very much affected by levels of stress. It’s onset usually occurs with a traumatic incident and it may be accompanied by another condition: ADHD, Tourette Syndrome, alcoholism, severe depression, schizophrenia, Autism, Bipolar Disorder. All of these are different manifestations of Pyroluria.

Pyroluria is a blood disorder. When the body creates hemoglobin there is a byproduct called kryptopyrroles. The kryptopyrroles in Pyroluria sufferers multiply too fast and block receptor sites for B-6 and zinc. This creates a serious deficiency of these two nutrients.

According to William Walsh of the Pfeiffer Treatment Center in Warrenville, IL: “Most persons with pyroluria respond very quickly to the B-6, Zn, C, E therapy… Major improvements are often seen by the 2nd day, and almost always by the end of the first week. The exceptions are:

  1. persons with severe mental illness (schizophrenia or bipolar)
  2. persons with other significant chemical imbalances
  3. patients with a major malabsorptive condition

When pyroluria is diagnosed along with another chemical imbalance, I like to track a patient during the first 6-8 weeks to determine which is the dominant imbalance. If major improvement occurs immediately, it’s because pyroluria has been corrected. Some patients report a nice early improvement followed by a plateau, and then another advance” [link].

If you believe you may suffer from Pyroluria it is best to speak with your doctor about it. It is always dangerous to treat yourself for any disease or disorder without the guidance of a medical professional. The information in this article is provided for informational purposes only and should not be used without proper testing and guidance from your medical doctor.

If you would like to visit a forum to learn more check out:

http://www.dr-bob.org/babble/alter/20050510/msgs/498689.html

http://brain.hastypastry.net/forums/showthread.php?p=9848#post9848

For additional information about Dr. Pfeiffer check out:

Nutrition and Mental Illness: An Orthomolecular Approach to Balancing Body Chemistry (Paperback) by Carl C. Pfeiffer

To learn more about Dr. Woody McGinnis and his work on the Mauve factor visit:

http://www.foodforthebrain.org/content.asp?id_Content=1693  to view the presentation, scroll down until you find Dr. Woody McGinnis and click.

http://www.alternativementalhealth.com/articles/pyroluria.htm

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Meet the Author

Caryn Talty
Caryn Talty
The editor of Healthy-family.org has a master's degree in English from Northern Illinois University and a bachelor of science degree in special education. She has taught students from early elementary school through college freshman level. Today she enjoys reading and writing about both hot topics and those not so commonly discussed on other websites. Most of her days are spent playing all kinds of make-believe with her three very young and active sons. | All articles by Caryn Talty.

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