I think the Natural Calm Magnesium works without the fizz. But we have made a lot of changes since we started him on the vits last year. For one thing he used to be a dairy-o-holic before we went gluten and corn free. I read that calcium competes with magnesium, so a diet too high in calcium will hinder magnesium absorption. When we cut out the gluten and corn he magically began to desire the dairy less and less. Weird huh? he still likes cheese, though, and we have to watch that. I will allow it in small doses. We originally used Bonnie's vits with magnesium taurate (supposedly more easily absorbed than citrate), but we also switched to the citrate version in a compounded capsule that was designed to combat Tigger's pyroluria dx. Eventually the vits started to make him nauseated (not uncommon if the vits are designed to compliment a dietary problem that is corrected-- in our case the gluten sensitive enteropathy was causing deficiencies in the body). Once Tigger's gut healed it seemed like his dependence on the vits lessened. We do eat a lot of beans and nuts here, which are high in magnesium. So is spinach, which we really only eat cooked but I am working on changing that. I recently read that swiss chard is high in magnesium too. Wow-- sounds like the perfect veggie for Tourette Syndrome! LOL.
At any rate, I really feel that magnesium is one supplement that we all can benefit from as our food comes from depleted soils (unless we are eating organic from our own soil) and that magnesium is just a necessary supplement for nervous system health. I take it, my mom does, my husband, all our kids in small doses.
So to answer your question I think it works synergistically with the better diet. I do not give Tigger B6 doses anymore (another vit for TS and pyroluria). I felt that it did something to trigger a phenol sensitivity in him and also contributed to his nausea (along with the high zinc doses). We eat a lot of bananas here, fish, and chicken breast. I feel that for right now I have no urgent need to up the B6 as he is not ticcing at all. If symptoms flare up I will, of course, resume the vits (for the pyroluria). It is an hereditary condition that is closely tied to the gut and is triggered by outside stress in life. He may get symptomatic when 'stuff happens' in his life and need to resume vits for a period of time. I am always watching out for that, but so far he is doing great. I have to also mention, for anyone who gets a pyroluria dx that the healing time for that can be 2 days to 2 months with vits, depending on the severity. Tigger had a mild case, thankfully!